ARCHIVE SEARCH
      -OR-  
 
  NEWS CHANNELS
Fitness News
 > Asthma Allergy News
Diabetes News
Women's Health News
Men's Health News

  MY NEWS
Personal Archive
My Account

  ABOUT THIS NEWSFEED
About Us
Advertise With Us
Feed Your Site
Contact Us


Site Map
RSS News Feed 

  Website development & hosting
   by Cyber Software Solutions

 
Penicillin Skin Testing Can ID Tolerance to β-Lactam Agents
Patients with reported history of penicillin allergy with negative PST tolerate β-lactam therapy

WEDNESDAY, June 19 (HealthDay News) -- Penicillin skin testing (PST) can be used to identify whether patients will tolerate β-lactam, with a negative predictive value of 100 percent, according to a study published in the June issue of the Journal of Hospital Medicine.

Ramzy H. Rimawi, M.D., from the Brody School of Medicine-East Carolina University in Greenville, N.C., and colleagues described the negative predictive value of PST and its impact on antibiotic selection in a sample of 146 patients with a reported history consistent with penicillin allergy and with negative PST. Patients were transitioned to treatment with a β-lactam agent.

The researchers found that only one of the patients experienced an allergic reaction to the PST. The remaining patients tolerated a full course of β-lactam therapy, with no evidence of allergic response. The negative predictive value for PST was 100 percent. PST-guided antibiotic alteration resulted in an estimated saving of $82,000 annually.

"Patients with a history of penicillin allergy who have a negative PST result are at a low risk of developing an immediate-type hypersensitivity reaction to β-lactam antibiotics," the authors write. "The increased use of PST may help improve antibiotic stewardship in the hospital setting."

One author disclosed financial ties to the pharmaceutical industry.

Abstract
Full Text (subscription or payment may be required)



Health News Copyright © 2013 HealthDay. All rights reserved.


Back to Top Stories
  GOOGLE ADS